Mechanistic basis and clinical relevance of the role of transforming growth factor-β in cancer
Transforming growth factor-β (TGF-β) is a key factor in cancer development and progression. TGF-β can suppress tumorigenesis by inhibiting cell cycle progression and stimulating apoptosis in early stages of cancer progression. However, TGF-β can modulate cancer-related processes, such as cell invasi...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
China Anti-Cancer Association
2015-12-01
|
Series: | Cancer Biology & Medicine |
Subjects: | |
Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/892 |