Recognition and receptor-mediated endocytosis of the lysosomal acid lipase secreted by cultured human fibroblasts.
We have studied the recognition and uptake of acid lipase by human fibroblasts in order to determine requirements for localization and function of the enzyme in lysosomes. Our approach was based on evidence that a number of acid hydrolases involved in mucopolysaccharide metabolism are secreted from...
Main Authors: | G N Sando, V L Henke |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
1982-01-01
|
Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520381803 |
Similar Items
-
Lysosomal trafficking of TGFBIp via caveolae-mediated endocytosis.
by: Seung-Il Choi, et al.
Published: (2015-01-01) -
Lysosomal Acid Lipase Deficiency: Therapeutic Options
by: Pastores GM, et al.
Published: (2020-02-01) -
Alterations in EGF-Endocytosis, Lysosomal Enzyme Transport and Maturation of Cathepsins in Juvenile Neuronal Ceroid Lipofuscinosis Fibroblasts
by: Jaime Cárcel-Trullols
Published: (2020-01-01) -
THE DISEASE IS THE ACCUMULATION OF CHOLESTEROL ESTERS DUE TO DEFICIT OF LYSOSOMAL ACID LIPASE. CLINICAL CASE OF LYSOSOMAL ACID LIPASE DEFICIENCY IS DESCRIBED IN THIS ARTICLE
by: S. A. Loskutova, et al.
Published: (2018-02-01) -
Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis
by: Yue-Wei Qian, et al.
Published: (2007-07-01)