Recognition and receptor-mediated endocytosis of the lysosomal acid lipase secreted by cultured human fibroblasts.
We have studied the recognition and uptake of acid lipase by human fibroblasts in order to determine requirements for localization and function of the enzyme in lysosomes. Our approach was based on evidence that a number of acid hydrolases involved in mucopolysaccharide metabolism are secreted from...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1982-01-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520381803 |