Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development

Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development

Deciphering how signaling pathways interact during development is necessary for understanding the etiopathogenesis of congenital malformations and disease. In several embryonic structures, components of the Hedgehog and retinoic acid pathways, two potent players in development and disease are expres...

Full description

Bibliographic Details
Main Authors: Maha El Shahawy, Claes-Göran Reibring, Kristina Hallberg, Cynthia L. Neben, Pauline Marangoni, Brian D. Harfe, Ophir D. Klein, Anders Linde, Amel Gritli-Linde
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
Cyp26 enzymes
congenital anomalies
CRE/LoxP
hedgehog signaling
mouse models
retinoic acid
smoothened
sonic hedgehog
Online Access:https://www.mdpi.com/1422-0067/20/9/2275

Internet

https://www.mdpi.com/1422-0067/20/9/2275

Similar Items