Anti–PD-1/PD-L1 Blockade Immunotherapy Employed in Treating Hepatitis B Virus Infection–Related Advanced Hepatocellular Carcinoma: A Literature Review

Anti–PD-1/PD-L1 Blockade Immunotherapy Employed in Treating Hepatitis B Virus Infection–Related Advanced Hepatocellular Carcinoma: A Literature Review

Hepatitis B virus (HBV) infection is regarded as the main etiological risk factor in the process of hepatocellular carcinoma (HCC), as it promotes an immunosuppressive microenvironment that is partially mediated by the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) signalin...

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Bibliographic Details
Main Authors: Bin Li, Cong Yan, Jiamin Zhu, Xiaobing Chen, Qihan Fu, Hangyu Zhang, Zhou Tong, Lulu Liu, Yi Zheng, Peng Zhao, Weiqin Jiang, Weijia Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
immunotherapy
hepatocellular carcinoma
hepatitis B virus
programmed cell death protein 1
programmed death-ligand 1
tumor microenvironment
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01037/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01037/full

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