Modeling Cu2+-Aβ complexes from computational approaches
Amyloid plaques formation and oxidative stress are two key events in the pathology of the Alzheimer disease (AD), in which metal cations have been shown to play an important role. In particular, the interaction of the redox active Cu2+ metal cation with Aβ has been found to interfere in amyloid aggr...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2015-09-01
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Series: | AIP Advances |
Online Access: | http://dx.doi.org/10.1063/1.4921072 |