Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.

Human γδ T cells are potent effectors against glioma cell lines in vitro and in human/mouse xenograft models of glioblastoma, however, this effect has not been investigated in an immunocompetent mouse model. In this report, we established GL261 intracranial gliomas in syngeneic WT C57BL/6 mice and m...

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Bibliographic Details
Main Authors: Benjamin H Beck, Hyunggoon Kim, Rebecca O'Brien, Martin R Jadus, G Yancey Gillespie, Gretchen A Cloud, Neil T Hoa, Catherine P Langford, Richard D Lopez, Lualhati E Harkins, Lawrence S Lamb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4425513?pdf=render