Bird to human transmission biases and vaccine escape mutants in H5N1 infections.

BACKGROUND:The avian influenza A H5N1 virus occasionally infects humans, with high mortality rates. Although all current human infections are from avian-to-human transmission, it has been shown that H5N1 can be evolved to transmit between mammals, and is therefore a pandemic threat. For H5N1 surveil...

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Bibliographic Details
Main Authors: Kshitij Wagh, Aatish Bhatia, Benjamin D Greenbaum, Gyan Bhanot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4079711?pdf=render