Picroside II attenuates fatty acid accumulation in HepG2 cells via modulation of fatty acid uptake and synthesis

Background/Aims Hepatic steatosis is caused by an imbalance between free fatty acids (FFAs) uptake, utilization, storage, and disposal. Understanding the molecular mechanisms involved in FFAs accumulation and its modulation could drive the development of potential therapies for Nonalcoholic fatty li...

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Main Authors: Hiteshi Dhami-Shah, Rama Vaidya, Shobha Udipi, Srividhya Raghavan, Shiny Abhijit, Viswanathan Mohan, Muthuswamy Balasubramanyam, Ashok Vaidya
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2018-03-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-2017-0039.pdf