Genome-wide survey of parent-of-origin-specific associations across clinical traits derived from electronic health records

Genome-wide survey of parent-of-origin-specific associations across clinical traits derived from electronic health records

Summary: Parent-of-origin (PoO) effects refer to the differential phenotypic impacts of genetic variants dependent on their parental inheritance due to imprinting. While PoO effects can influence complex traits, they may be poorly captured by models that do not differentiate the parental origin of t...

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Bibliographic Details
Main Authors: Hye In Kim, Bin Ye, Jeffrey Staples, Anthony Marcketta, Chuan Gao, Alan R. Shuldiner, Cristopher V. Van Hout
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:HGG Advances
Subjects:
parent-of-origin effect
imprinting
familial relationship
GWAS
electronic health record
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247721000208

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http://www.sciencedirect.com/science/article/pii/S2666247721000208

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