In vitro wound healing of tumor cells: inhibition of cell migration by selected cytotoxic alkaloids

In vitro wound healing of tumor cells: inhibition of cell migration by selected cytotoxic alkaloids

Abstract Background Cell migration is involved in several pathological processes such as tumor invasion, neoangiogenesis and metastasis. Microtubules are needed in directional migration. Methods To investigate the effects of microtubule-binding agents (paclitaxel, vinblastine, colchicine, podophyllo...

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Bibliographic Details
Main Authors: Xiaojuan Wang, Charlotte Caroline Decker, Laura Zechner, Sonja Krstin, Michael Wink
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Cell migration
Microtubule
In vitro wound healing assay
Microtubule-binding agents
Benzophenanthridine alkaloids
Homoharringtonine
Online Access:http://link.springer.com/article/10.1186/s40360-018-0284-4

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http://link.springer.com/article/10.1186/s40360-018-0284-4

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