Dorsal striatum and its limbic connectivity mediate abnormal anticipatory reward processing in obesity.

Obesity is characterized by an imbalance in the brain circuits promoting reward seeking and those governing cognitive control. Here we show that the dorsal caudate nucleus and its connections with amygdala, insula and prefrontal cortex contribute to abnormal reward processing in obesity. We measured...

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Bibliographic Details
Main Authors: Lauri Nummenmaa, Jussi Hirvonen, Jarna C Hannukainen, Heidi Immonen, Markus M Lindroos, Paulina Salminen, Pirjo Nuutila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3272045?pdf=render