HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer

HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer

Tumors acquire numerous mutations during development and progression. When translated into proteins, these mutations give rise to neoantigens that can be recognized by T cells and generate antibodies, representing an exciting direction of cancer immunotherapy. While neoantigens have been reported in...

Full description

Bibliographic Details
Main Authors: Yingxue Ren, Yesesri Cherukuri, Daniel P. Wickland, Vivekananda Sarangi, Shulan Tian, Jodi M. Carter, Aaron S. Mansfield, Matthew S. Block, Mark E. Sherman, Keith L. Knutson, Yi Lin, Yan W. Asmann
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
breast cancer
neoantigen
overall survival
tumor mutational burden
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1744947

Internet

http://dx.doi.org/10.1080/2162402X.2020.1744947

Similar Items