LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients

LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients

Abstract Background The low-density lipoprotein receptor (LDLR) plays a significant role in maintaining the cellular cholesterol homeostasis. Mutations in the LDLR gene can lead to a significant rise in plasma LDL levels that may result in an increased risk of atherosclerosis and coronary heart dise...

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Bibliographic Details
Main Authors: Monika Buraczynska, Jerry Jacob, Karolina Gwiazda-Tyndel, Andrzej Ksiazek
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Nephrology
Subjects:
LDL receptor gene
End-stage kidney disease
rs688 polymorphism
Genotyping
Risk allele
Online Access:https://doi.org/10.1186/s12882-021-02532-6

Internet

https://doi.org/10.1186/s12882-021-02532-6

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