FGF/FGFR Pathways in Multiple Sclerosis and in Its Disease Models

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system (CNS) affecting more than two million people worldwide. In MS, oligodendrocytes and myelin sheaths are destroyed by autoimmune-mediated inflammation, while remyelination is impaired. Recent...

Full description

Bibliographic Details
Main Authors: Ranjithkumar Rajendran, Gregor Böttiger, Christine Stadelmann, Srikanth Karnati, Martin Berghoff
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
FGF
EAE
ERK
Akt
Online Access:https://www.mdpi.com/2073-4409/10/4/884