Sphingosine-1-phosphate transport and its role in immunology

Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite with many important functions in cellular and systemic physiology, including the immune system. As it cannot traverse the membrane, it is exported from cells by transporters. Several members of the ATP-binding cassette (ABC) transporter fami...

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Bibliographic Details
Main Authors: Vera Reitsema, Hjalmar Bouma, Jan Willem Kok
Format: Article
Language:English
Published: AIMS Press 2014-12-01
Series:AIMS Molecular Science
Subjects:
S1P
Online Access:http://www.aimspress.com/article/10.3934/molsci.2014.4.183/fulltext.html