Dihydromyricetin attenuates Escherichia coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3 inflammasome and TLR4/NF-κB signalling pathway

Dihydromyricetin attenuates Escherichia coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3 inflammasome and TLR4/NF-κB signalling pathway

Abstract Lipopolysaccharide (LPS) as a major component of Escherichia coli cell wall can cause inflammation and cell death. Dihydromyricetin (ampelopsin, DHM) is a natural flavonoid compound with anti-inflammatory, anti-oxidant and anti-bacterial effects. The preventive effects of DHM against ileum...

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Bibliographic Details
Main Authors: Yicong Chang, Liang Yuan, Jiarui Liu, Ishfaq Muhammad, Chuanbao Cao, Chenxi Shi, Yuanyuan Zhang, Rui Li, Changwen Li, Fangping Liu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-020-00796-8

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http://link.springer.com/article/10.1186/s13567-020-00796-8

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