Reactive T Cells in Convalescent COVID-19 Patients With Negative SARS-CoV-2 Antibody Serology

Reactive T Cells in Convalescent COVID-19 Patients With Negative SARS-CoV-2 Antibody Serology

Despite RT-PCR confirmed COVID-19, specific antibodies to SARS-CoV-2 spike are undetectable in serum in approximately 10% of convalescent patients after mild disease course. This raises the question of induction and persistence of SARS-CoV-2-reactive T cells in these convalescent individuals. Using...

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Bibliographic Details
Main Authors: Sophie Steiner, Tatjana Schwarz, Victor M. Corman, Franziska Sotzny, Sandra Bauer, Christian Drosten, Hans-Dieter Volk, Carmen Scheibenbogen, Leif G. Hanitsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
coronavirus disease 2019 (COVID-19)
T cell response
seronegative
antibody response
human endemic coronavirus 229E (HCoV-229E)
human endemic coronavirus OC43 (HCoV-OC43)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687449/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.687449/full

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