The Circadian Clock Gates the Intestinal Stem Cell Regenerative State

The intestine has evolved under constant environmental stresses, because an animal may ingest harmful pathogens or chemicals at any time during its lifespan. Following damage, intestinal stem cells (ISCs) regenerate the intestine by proliferating to replace dying cells. ISCs from diverse animals ar...

Full description

Bibliographic Details
Main Authors: Phillip Karpowicz, Yong Zhang, John B. Hogenesch, Patrick Emery, Norbert Perrimon
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471300123X