Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study

Aldose reductase (AR) inhibitors have vital importance in the treatment and prevention of diabetic complications. In this study, rat kidney AR was purified 19.34-fold with a yield of 3.49% and a specific activity of 0.88 U/mg using DE-52 Cellulose anion exchange chromatography, gel filtration chroma...

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Bibliographic Details
Main Authors: Zuhal Alim, Namik Kilinç, Bülent Şengül, Şükrü Beydemir
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:http://dx.doi.org/10.1080/14756366.2016.1250752