Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion.

Fibrinogen is an essential part of the blood coagulation cascade and a major component of the extracellular matrix in mammals. The interface between fibrinogen and bacterial pathogens is an important determinant of the outcome of infection. Here, we demonstrate that a canine host-restricted skin pat...

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Bibliographic Details
Main Authors: Amy C Pickering, Pauline Vitry, Valeriia Prystopiuk, Brandon Garcia, Magnus Höök, Jeffrey Schoenebeck, Joan A Geoghegan, Yves F Dufrêne, J Ross Fitzgerald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007816