Sulfotyrosine Recognition as Marker for Druggable Sites in the Extracellular Space

Chemokine signaling is a well-known agent of autoimmune disease, HIV infection, and cancer. Drug discovery efforts for these signaling molecules have focused on developing inhibitors targeting their associated G protein-coupled receptors. Recently, we used a structure-based approach directed at the...

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Bibliographic Details
Main Authors: Brian F. Volkman, Francis C. Peterson, Christopher T. Veldkamp, Maxime S. Heroux, Joshua J. Ziarek
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/12/6/3740/