Role of miR-200c in Myogenic Differentiation Impairment via p66Shc: Implication in Skeletal Muscle Regeneration of Dystrophic mdx Mice

Role of miR-200c in Myogenic Differentiation Impairment via p66Shc: Implication in Skeletal Muscle Regeneration of Dystrophic mdx Mice

Duchenne muscular dystrophy (DMD) is a genetic disease associated with mutations of Dystrophin gene that regulate myofiber integrity and muscle degeneration, characterized by oxidative stress increase. We previously published that reactive oxygen species (ROS) induce miR-200c that is responsible for...

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Bibliographic Details
Main Authors: Marco D’Agostino, Alessio Torcinaro, Luca Madaro, Lorenza Marchetti, Sara Sileno, Sara Beji, Chiara Salis, Daisy Proietti, Giulia Imeneo, Maurizio C. Capogrossi, Francesca De Santa, Alessandra Magenta
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/4814696

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http://dx.doi.org/10.1155/2018/4814696

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