Identification of conserved and HLA promiscuous DENV3 T-cell epitopes.

Anti-dengue T-cell responses have been implicated in both protection and immunopathology. However, most of the T-cell studies for dengue include few epitopes, with limited knowledge of their inter-serotype variation and the breadth of their human leukocyte antigen (HLA) affinity. In order to expand...

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Bibliographic Details
Main Authors: Eduardo J M Nascimento, Robbie B Mailliard, Asif M Khan, John Sidney, Alessandro Sette, Nicole Guzman, Michael Paulaitis, Andréa Barbosa de Melo, Marli T Cordeiro, Laura V G Gil, Françoir Lemonnier, Charles Rinaldo, J Thomas August, Ernesto T A Marques
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3794980?pdf=render