Intrahepatic macrophage populations in the pathophysiology of primary sclerosing cholangitis

Background & Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammatory and fibrotic injury to the biliary tree. We sought to further delineate the contribution of macrophage lineages in PSC pathobiology. Methods: Human liver tissu...

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Bibliographic Details
Main Authors: Yung-Yi Chen, Kathryn Arndtz, Gwilym Webb, Margaret Corrigan, Sarah Akiror, Evaggelia Liaskou, Paul Woodward, David H. Adams, Chris J. Weston, Gideon M. Hirschfield
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:JHEP Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555919301259