Mechanisms and microbial influences on CTLA-4 and PD-1-based immunotherapy in the treatment of cancer: a narrative review

Abstract Background The relationship between gastrointestinal (GI) bacteria and the response to anti-CTLA-4 and anti-PD-1 immunotherapy in the treatment of cancer can potentially be enhanced to allow patients to maximally respond to these treatments. Insight into the complex interaction between gut...

Full description

Bibliographic Details
Main Authors: Peter L. Miller, Tiffany L. Carson
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Gut Pathogens
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13099-020-00381-6