Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Human RNA editing enzymes ADAR1 and ADAR2 are required for innate immune functions and neurological functions, respectively. Here, the authors show that Drosophila Adar has both innate immune and brain functions, despite being the homolog of mammalian ADAR2.

Bibliographic Details
Main Authors: Patricia Deng, Anzer Khan, Dionna Jacobson, Nagraj Sambrani, Leeanne McGurk, Xianghua Li, Aswathy Jayasree, Jan Hejatko, Galit Shohat-Ophir, Mary A. O’Connell, Jin Billy Li, Liam P. Keegan
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15435-1

Internet

https://doi.org/10.1038/s41467-020-15435-1

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