Local administration of ReveromycinA ointment suppressed alveolar bone loss in mice

Local administration of ReveromycinA ointment suppressed alveolar bone loss in mice

ReveromycinA (RMA) was developed and is a unique agent for inhibiting osteoclast activity. In a previous study, we experimentally induced periodontal disease in a high-turnover osteoporosis osteoprotegerin-knockout mice (OPG KO) model and found that intraperitoneal administration of RMA inhibited al...

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Bibliographic Details
Main Authors: Ken Miyazawa, Yuichiro Asano, Masako Tabuchi, Shunsuke Kako, Makoto Kawatani, Hiroyuki Osada, Hatsuhiko Maeda, Shigemi Goto
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Periodontal disease(s)/Periodontitis
Drug delivery
Osteoclast(s)
Bone remodeling/regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000530

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http://www.sciencedirect.com/science/article/pii/S1347861321000530

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