Impact of RB1 gene mutation type in retinoblastoma patients on clinical presentation and management outcome

Impact of RB1 gene mutation type in retinoblastoma patients on clinical presentation and management outcome

Objective/background: Retinoblastoma (RB), the most common intraocular malignancy in children, is caused by biallelic inactivation of the human retinoblastoma susceptibility gene (RB1). We are evaluating the impact of the type of RB1 gene mutation on clinical presentation and management outcome. Met...

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Bibliographic Details
Main Authors: Mustafa Mehyar, Mohammad Mosallam, Abdelghani Tbakhi, Ala Saab, Iyad Sultan, Rasha Deebajah, Imad Jaradat, Reem AlJabari, Mona Mohammad, Ibrahim AlNawaiseh, Maysa Al-Hussaini, Yacoub A. Yousef
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
Germline
Mutation
RB1 gene
Retinoblastoma
Online Access:http://www.sciencedirect.com/science/article/pii/S165838762030039X

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http://www.sciencedirect.com/science/article/pii/S165838762030039X

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