Refinement of a mouse cardiovascular model: Development, application and dissemination [version 1; referees: 2 approved, 1 approved with reservations]

European and UK legislation requires all animal procedures to be conducted with consideration to reduction, refinement and replacement. In this review, 3Rs developments are discussed in the field of platelet biology and thromboembolism. Platelet research requires the use of animal models, and mice a...

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Bibliographic Details
Main Authors: Kirk A. Taylor, Michael Emerson
Format: Article
Language:English
Published: F1000 Research Ltd 2018-05-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-593/v1