A phase II study of gemcitabine combined with vinorelbine as first-line chemotherapy for metastatic breast cancer

BACKGROUND AND OBJECTIVES: There is an unmet need for new combination treatments, especially for aggressive, visceral, and high tumor burden metastatic breast cancer. Gemcitabine (GEM) has shown synergy with vinorelbine (VRL) in preclinical models, and has a toxicity profile that is different from V...

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Bibliographic Details
Main Authors: Samir Shehata, Ebtesam Saad, Yasser Goda, Salah El-Mesidi, Hanaa Koheil, Heba Elzawhri, Alaa Kandeel, Thoraya Abdelhamid, Mounir Zaki, Mohamed Meshref
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387610500499