Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network.

Regulatory T cells (Treg) are essential for T cell homeostasis and maintenance of peripheral tolerance. They prevent activation of auto-reactive T effector cells (Teff) in the context of autoimmunity and allergy. Otherwise, Treg also inhibit effective immune responses against tumors. Besides a numbe...

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Bibliographic Details
Main Authors: Andrea Tuettenberg, Susanne A Hahn, Johanna Mazur, Aslihan Gerhold-Ay, Jetse Scholma, Iris Marg, Alexander Ulges, Kazuki Satoh, Tobias Bopp, Jos Joore, Helmut Jonuleit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4755507?pdf=render