Immune response and mitochondrial metabolism are commonly deregulated in DMD and aging skeletal muscle.

Duchenne Muscular Dystrophy (DMD) is a complex process involving multiple pathways downstream of the primary genetic insult leading to fatal muscle degeneration. Aging muscle is a multifactorial neuromuscular process characterized by impaired muscle regeneration leading to progressive atrophy. We hy...

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Bibliographic Details
Main Authors: Daniel Baron, Armelle Magot, Gérard Ramstein, Marja Steenman, Guillemette Fayet, Catherine Chevalier, Philippe Jourdon, Rémi Houlgatte, Frédérique Savagner, Yann Pereon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3212519?pdf=render