Linking transcriptional changes over time in stimulated dendritic cells to identify gene networks activated during the innate immune response.

The innate immune response is primarily mediated by the Toll-like receptors functioning through the MyD88-dependent and TRIF-dependent pathways. Despite being widely studied, it is not yet completely understood and systems-level analyses have been lacking. In this study, we identified a high-probabi...

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Bibliographic Details
Main Authors: Ashwini Patil, Yutaro Kumagai, Kuo-Ching Liang, Yutaka Suzuki, Kenta Nakai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3820512?pdf=render