Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia

SUMMARY Obesity is a complex metabolic disorder that often manifests with a strong genetic component in humans. However, the genetic basis for obesity and the accompanying metabolic syndrome is poorly defined. At a metabolic level, obesity arises from an imbalance between the nutritional intake and...

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Bibliographic Details
Main Authors: Manivannan Subramanian, Suman Kumar Metya, Sufia Sadaf, Satish Kumar, Dominik Schwudke, Gaiti Hasan
Format: Article
Language:English
Published: The Company of Biologists 2013-05-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/3/734