A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/Yorkie (Yki), has been implicated in many cancers,...

Full description

Bibliographic Details
Main Authors: Anjali Bajpai, Taushif Ahmad Quazi, Hong-Wen Tang, Nishat Manzar, Virender Singh, Ashwani Thakur, Bushra Ateeq, Norbert Perrimon, Pradip Sinha
Format: Article
Language:English
Published: The Company of Biologists 2020-07-01
Series:Disease Models & Mechanisms
Subjects:
drosophila
peptide therapeutic
yki
intestinal stem cells
integrin signaling
Online Access:http://dmm.biologists.org/content/13/7/dmm044420

Internet

http://dmm.biologists.org/content/13/7/dmm044420

Similar Items