Metagenomic Next Generation Sequencing in the Detection of Pathogens in Cerebrospinal Fluid of Patients After Alternative Donor Transplantation: A Feasibility Analysis

Metagenomic Next Generation Sequencing in the Detection of Pathogens in Cerebrospinal Fluid of Patients After Alternative Donor Transplantation: A Feasibility Analysis

Central nervous system (CNS) complications can occur in 9%–15% of patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The clinical manifestations of the CNS complications are non-specific, with most of them being disturbances of consciousness, convulsions, headaches, fever...

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Bibliographic Details
Main Authors: Binglei Zhang, Jian Zhou, Ruirui Gui, Zhen Li, Yingling Zu, Juan Wang, Fengkuan Yu, Yanli Zhang, Huifang Zhao, Zhenyu Ji, Yongping Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomics next generation sequencing (mNGS)
alternative donor
hematopoietic stem cell transplantation
cerebrospinal fluid
pathogen
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.720132/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.720132/full

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