Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process.

Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process.

Despite large vaccination campaigns, measles virus (MeV) and canine distemper virus (CDV) cause major morbidity and mortality in humans and animals, respectively. The MeV and CDV cell entry system relies on two interacting envelope glycoproteins: the attachment protein (H), consisting of stalk and h...

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Bibliographic Details
Main Authors: Nadine Ader-Ebert, Mojtaba Khosravi, Michael Herren, Mislay Avila, Lisa Alves, Fanny Bringolf, Claes Örvell, Johannes P Langedijk, Andreas Zurbriggen, Richard K Plemper, Philippe Plattet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4422687?pdf=render

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http://europepmc.org/articles/PMC4422687?pdf=render

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