A Novel Role for Triglyceride Metabolism in Foxp3 Expression

Lipid metabolism plays a key role in many cellular processes. We show here that regulatory T cells have enhanced lipid storage within subcellular lipid droplets (LD). They also express elevated amounts of both isoforms of diacylglycerol acyl transferase (DGAT1 & 2), enzymes required for the...

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Bibliographic Details
Main Authors: Duncan Howie, Annemieke Ten Bokum, Stephen Paul Cobbold, Zhanru Yu, Benedikt M. Kessler, Herman Waldmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01860/full