Prediction of porcine interferon α antiviral activity in fermentation by Pichia pastoris based on multivariable regression and artificial neural network

Prediction of porcine interferon α antiviral activity in fermentation by Pichia pastoris based on multivariable regression and artificial neural network

One of the most important methods to produce porcine interferon α is microbial fermentation. In the present study, recombinant Pichia pastoriswas used. Broth’s antiviral activity is the key index of the expression level of porcine interferon α. Measurement of antiviral activity is a time-co...

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Bibliographic Details
Main Authors: Ding Jian, Wang Huihui, Dai Keke, Zi Yuhua, Shi Zhongping
Format: Article
Language:English
Published: Association of the Chemical Engineers of Serbia 2014-01-01
Series:Chemical Industry and Chemical Engineering Quarterly
Subjects:
porcine interferon α
antiviral activity
multivariable regression
artificial neural network
back-propagation algorithm
genetic algorithm
Online Access:http://www.doiserbia.nb.rs/img/doi/1451-9372/2014/1451-93721200097D.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/1451-9372/2014/1451-93721200097D.pdf

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