Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.

Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.

BACKGROUND: Environmental enrichment (EE) in laboratory animals improves neurological function and motor/cognitive performance, and is proposed as a strategy for treating neurodegenerative diseases. EE has been investigated in the R6/2 mouse model of Huntington's disease (HD), where increased s...

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Bibliographic Details
Main Authors: Nigel I Wood, Valentina Carta, Stefan Milde, Elizabeth A Skillings, Catherine J McAllister, Y L Mabel Ang, Alasdair Duguid, Nadeev Wijesuriya, Samira Mohd Afzal, Joe X Fernandes, T W Leong, A Jennifer Morton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2820540?pdf=render

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http://europepmc.org/articles/PMC2820540?pdf=render

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