Genomic and Transcriptomic Characteristics of Esophageal Adenocarcinoma

Genomic and Transcriptomic Characteristics of Esophageal Adenocarcinoma

Esophageal adenocarcinoma (EAC) is a deadly disease with limited options for targeted therapy. With the help of next-generation sequencing studies over the last decade, we gained an understanding of the genomic architecture of EAC. The tumor suppressor gene <i>TP53</i> is mutated in 70 t...

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Bibliographic Details
Main Authors: Sascha Hoppe, Christoph Jonas, Marten Christian Wenzel, Oscar Velazquez Camacho, Christoph Arolt, Yue Zhao, Reinhard Büttner, Alexander Quaas, Patrick Sven Plum, Axel Maximilian Hillmer
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
esophageal adenocarcinoma
genomics
transcriptomics
mutation
tumor development
Barrett’s esophagus
Online Access:https://www.mdpi.com/2072-6694/13/17/4300

Internet

https://www.mdpi.com/2072-6694/13/17/4300

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