A novel fusogenic herpes simplex virus for oncolytic virotherapy of squamous cell carcinoma

A novel fusogenic herpes simplex virus for oncolytic virotherapy of squamous cell carcinoma

<p>Abstract</p> <p>Background</p> <p>R849 is a neurovirulent γ<sub>1</sub>34.5 gene-deficient form of herpes simplex virus type 1 (HSV-1) and has LacZ genes at the deleted sites of the γ<sub>1</sub>34.5 gene. HF is a spontaneously occurring, fuso...

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Bibliographic Details
Main Authors: Iwai Soichi, Imai Tomoaki, Ogawa Fumi, Takahashi Gen, Takaoka Hiroo, Yura Yoshiaki
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Virology Journal
Subjects:
herpes simplex virus mutant
oncolytic virotherapy
oral squamous cell carcinoma
cell fusion
Online Access:http://www.virologyj.com/content/8/1/294

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http://www.virologyj.com/content/8/1/294

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