Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest

Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest

<p>Abstract</p> <p>Background</p> <p>Cell division cycle associated 3 (CDCA3), part of the Skp1-cullin-F-box (SCF) ubiquitin ligase, refers to a trigger of mitotic entry and mediates destruction of the mitosis inhibitory kinase. Little is known about the relevance of CD...

Full description

Bibliographic Details
Main Authors: Uchida Fumihiko, Uzawa Katsuhiro, Kasamatsu Atsushi, Takatori Hiroaki, Sakamoto Yosuke, Ogawara Katsunori, Shiiba Masashi, Tanzawa Hideki, Bukawa Hiroki
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Cancer
Subjects:
Cell division cycle associated 3
Oral squamous cell carcinoma
Proliferation
Cell-cycle arrest
Cyclin-dependent kinase inhibitors
Online Access:http://www.biomedcentral.com/1471-2407/12/321

Internet

http://www.biomedcentral.com/1471-2407/12/321

Similar Items