Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination

Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination

Porcine deltacoronavirus (PDCoV) is a newly detected porcine coronavirus causing serious vomiting and diarrhea in piglets, especially newborn piglets. There has been an outbreak of PDCoV in worldwide since 2014, causing significant economic losses in the pig industry. The interferon (IFN)-mediated a...

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Bibliographic Details
Main Authors: Ji Likai, Li Shasha, Zhu Wenxian, Ma Jingjiao, Sun Jianhe, Wang Hengan, Yan Yaxian
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
PDCoV
nucleocapsid protein
porcine RIG-I
IFN-β
ubiquitination
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01024/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01024/full

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