Roles of Voltage-Gated Tetrodotoxin-Sensitive Sodium Channels NaV1.3 and NaV1.7 in Diabetes and Painful Diabetic Neuropathy

Roles of Voltage-Gated Tetrodotoxin-Sensitive Sodium Channels NaV1.3 and NaV1.7 in Diabetes and Painful Diabetic Neuropathy

Diabetes mellitus (DM) is a common chronic medical problem worldwide; one of its complications is painful peripheral neuropathy, which can substantially erode quality of life and increase the cost of management. Despite its clinical importance, the pathogenesis of painful diabetic neuropathy (PDN) i...

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Bibliographic Details
Main Authors: Linlin Yang, Quanmin Li, Xinming Liu, Shiguang Liu
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes mellitus
painful diabetic neuropathy
NaV1.3
NaV1.7
dorsal root ganglion neurons
pancreatic islet cells
Online Access:http://www.mdpi.com/1422-0067/17/9/1479

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http://www.mdpi.com/1422-0067/17/9/1479

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