Anti-breast Cancer Enhancement of a Polysaccharide From Spore of Ganoderma lucidum With Paclitaxel: Suppression on Tumor Metabolism With Gut Microbiota Reshaping

Anti-breast Cancer Enhancement of a Polysaccharide From Spore of Ganoderma lucidum With Paclitaxel: Suppression on Tumor Metabolism With Gut Microbiota Reshaping

Increasing evidence highlights the cardinal role of gut microbiota in tumorigenesis and chemotherapy outcomes. Paclitaxel (PTX), although as a first-line chemotherapy reagent for breast cancer, still requires for improvement on its efficacy and safety due to drug resistance and adverse effects. The...

Full description

Bibliographic Details
Main Authors: Jiyan Su, Dan Li, Qianjun Chen, Muxia Li, Lu Su, Ting Luo, Danling Liang, Guoxiao Lai, Ou Shuai, Chunwei Jiao, Qingping Wu, Yizhen Xie, Xinxin Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
spore of Ganoderma lucidum
paclitaxel
tumor metabolism
immune checkpoints
gut microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03099/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03099/full

Similar Items