Clinicopathological Characteristics and Mutations Driving Development of Early Lung Adenocarcinoma: Tumor Initiation and Progression

Clinicopathological Characteristics and Mutations Driving Development of Early Lung Adenocarcinoma: Tumor Initiation and Progression

Lung cancer is the leading cause of cancer-related deaths worldwide, with lung adenocarcinoma representing the most common lung cancer subtype. Among all lung adenocarcinomas, the most prevalent subset develops via tumorigenesis and progression from atypical adenomatous hyperplasia (AAH) to adenocar...

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Bibliographic Details
Main Author: Kentaro Inamura
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
CDKN2A (p16)
de novo pathway
HNF4A
immunohistochemistry
molecular pathological epidemiology
NKX2-1 (TTF-1) amplification
Napsin A
Noguchi classification
terminal respiratory unit (TRU)-lineage
TP53 (p53)
Online Access:http://www.mdpi.com/1422-0067/19/4/1259

Internet

http://www.mdpi.com/1422-0067/19/4/1259

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