Geometric cues stabilise long-axis polarisation of PAR protein patterns in C. elegans

In the C. elegans zygote, (anterior) aPAR and (posterior) pPAR proteins are key to polarity maintenance, what factors determine the selection of the polarity axis remains unclear. Here authors formulate a reaction-diffusion model in realistic cell geometry and find that long-axis polarisation is pro...

Full description

Bibliographic Details
Main Authors: Raphaela Geßele, Jacob Halatek, Laeschkir Würthner, Erwin Frey
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14317-w