Significantly improved HIV inhibitor efficacy prediction employing proteochemometric models generated from antivirogram data.

Significantly improved HIV inhibitor efficacy prediction employing proteochemometric models generated from antivirogram data.

Infection with HIV cannot currently be cured; however it can be controlled by combination treatment with multiple anti-retroviral drugs. Given different viral genotypes for virtually each individual patient, the question now arises which drug combination to use to achieve effective treatment. With t...

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Bibliographic Details
Main Authors: Gerard J P van Westen, Alwin Hendriks, Jörg K Wegner, Adriaan P Ijzerman, Herman W T van Vlijmen, Andreas Bender
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3578754?pdf=render

Internet

http://europepmc.org/articles/PMC3578754?pdf=render

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